Rambo: Last Blood saw Stallone's Rambo go after a cartel who drugged and kidnapped his niece. The original script had a few similarities but it saw the return of Brian Dennehy (he was still alive when it was written) as the main bad guy harking back to the first film
This version saw Rambo living as a recluse in Arizona, who reluctantly agrees to head to Mexico to look into the disappearance of his maid's missing granddaughter, who was trying to cross the border. Rambo heads to Mexico and discovers the girl was kidnapped by sex traffickers, and he's horrified to learn the man in charge - dubbed "The Judge" - is none other than Will Teasle, the sheriff who became his nemesis in First Blood.
Teasle was played by Brian Dennehy, and while not an out-and-out bad guy, he is depicted as a cruel bully whose needless mistreatment of Rambo is what led to the latter's rampage. The original movie ended with Rambo sparring the sheriff's life after a violent showdown, but Rambo: Borderline's screenplay revealed he ended up in Mexico and became a vicious crime boss. This makes Rambo's war in this version especially personal, as he feels responsible for all the chaos and trauma Teasle has wrought in the years since he sparred him.
Credit Screen Rant for article